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Specific Comment

Average Peer review marks at initial stage: 6.66/10

Average Peer review marks at publication stage: 9/10

Stage 1 |Original Manuscript | File 1 | NA

Stage 2 |Peer review report_1 (Tong Yuxin  , China) | File 1 | NA

Stage 2 | Peer review report_2 (Chao Zhao Key Lab Med Mol Virol, China) | File 1 | NA

Stage 2 |Peer review report_3 (Martí Rufí-Salís, Spain) | File 1 | NA

Stage 2 | Revised_MS_v1_and_Feedback_v1| File 1 | File 2

Stage 3 | Comment_Editor_1_v1 | File 1 | NA

Stage 3 | Revised_MS_v2_and_Feedback_v2 | File 1 | NA